Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC7186423 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Liu Xiaomei X Wang Yuxi Y Zhang Rong R Jin Ting T Qu Liangliang L Jin Qianwen Q Zheng Jiasu J Sun Jiaqi J Wu Ziqing Z Wang Linxi L Liu Tianxu T Zhang Yinxu Y Meng Xiao X Wang Ying Y Wei Ning N
Frontiers in oncology 20200421
Currently, non-small cell lung carcinoma (NSCLC) is a major worldwide health problem. Meanwhile accumulating evidence indicates that histone deacetylase (HDAC) activation could induce PD-L1 expression in various types of cancer, especially in myeloma and B-cell lymphomas. Therefore, we hypothesized that high-level expression of HDAC10 is associated with PD-L1 induction and poor prognosis in patients with NSCLC. In total 180 NSCLC patients receiving complete pulmonary resection and systematic lym ...[more]