Ontology highlight
ABSTRACT:
SUBMITTER: Urabe F
PROVIDER: S-EPMC7190312 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Urabe Fumihiko F Kosaka Nobuyoshi N Sawa Yurika Y Yamamoto Yusuke Y Ito Kagenori K Yamamoto Tomofumi T Kimura Takahiro T Egawa Shin S Ochiya Takahiro T
Science advances 20200429 18
Extracellular vesicles (EVs) are involved in intercellular communication during cancer progression; thus, elucidating the mechanism of EV secretion in cancer cells will contribute to the development of an EV-targeted cancer treatment. However, the biogenesis of EVs in cancer cells is not fully understood. MicroRNAs (miRNAs) regulate a variety of biological phenomena; thus, miRNAs could regulate EV secretion. Here, we performed high-throughput miRNA-based screening to identify the regulators of E ...[more]