Ontology highlight
ABSTRACT:
SUBMITTER: Hersman S
PROVIDER: S-EPMC7190350 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Hersman Sarah S Allen David D Hashimoto Mariko M Brito Salvador Ignacio SI Anthony Todd E TE
eLife 20200327
Assessing the imminence of threatening events using environmental cues enables proactive engagement of appropriate avoidance responses. The neural processes employed to anticipate event occurrence depend upon which cue properties are used to formulate predictions. In serial compound stimulus (SCS) conditioning in mice, repeated presentations of sequential tone (CS1) and white noise (CS2) auditory stimuli immediately prior to an aversive event (US) produces freezing and flight responses to CS1 an ...[more]