Ontology highlight
ABSTRACT:
SUBMITTER: Dubey S
PROVIDER: S-EPMC7190353 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Dubey Sushil S Bhembre Nishita N Bodas Shivani S Veer Sukh S Ghose Aurnab A Callan-Jones Andrew A Pullarkat Pramod P
eLife 20200408
Axons span extreme distances and are subject to significant stretch deformations during limb movements or sudden head movements, especially during impacts. Yet, axon biomechanics, and its relation to the ultrastructure that allows axons to withstand mechanical stress, is poorly understood. Using a custom developed force apparatus, we demonstrate that chick dorsal root ganglion axons exhibit a tension buffering or strain-softening response, where its steady state elastic modulus decreases with in ...[more]