Cation-induced shape programming and morphing in protein-based hydrogels.

ABSTRACT: Smart materials that are capable of memorizing a temporary shape, and morph in response to a stimulus, have the potential to revolutionize medicine and robotics. Here, we introduce an innovative method to program protein hydrogels and to induce shape changes in aqueous solutions at room temperature. We demonstrate our approach using hydrogels made from serum albumin, the most abundant protein in the blood plasma, which are synthesized in a cylindrical or flower shape. These gels are then programmed into a spring or a ring shape, respectively. The programming is performed through a marked change in stiffness (of up to 17-fold), induced by adsorption of Zn²⁺ or Cu²⁺ cations. We show that these programmed biomaterials can then morph back into their original shape, as the

SUBMITTER: Khoury LR 

PROVIDER: S-EPMC7190360 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature