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Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction.

ABSTRACT: A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels-Alder reaction.

SUBMITTER: Yu H

PROVIDER: S-EPMC7191567 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction.

Yu Huangchao H Fought Ellie L EL Windus Theresa L TL Kraus George A GA

ACS omega 20200417 16

A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels-Alder reaction. ...[more]

PMID: 32363281

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