Serum albumin concentration and risk of end-stage renal disease: the REGARDS study.

ABSTRACT:

Background

Serum albumin concentration is a commonly available biomarker with prognostic value in many disease states. It is uncertain whether serum albumin concentrations are associated with incident end-stage renal disease (ESRD) independently of urine albumin-to-creatinine ratio (ACR).

Methods

A longitudinal evaluation was performed of a population-based community-living cohort from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Participants were ≥45 years of age at study entry and had serum albumin, creatinine, cystatin C and spot urine ACR measured at the baseline visit (n = 19 633). Estimated glomerular filtration rate (eGFR) was from the Chronic Kidney Disease Epidemiology Collaboration combined creatinine-cystatin C equation. Baseline se

SUBMITTER: Walther CP 

PROVIDER: S-EPMC7191876 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature