Dataset Information

Non-linear relationship between basal serum albumin concentration and cardiac arrest in critically ill patients with end-stage renal disease: a cross-sectional study.

ABSTRACT:

Objectives

The aim of our study was to investigate the association between serum albumin concentration and the risk of cardiac arrest in critically ill patients with end-stage renal disease in the intensive care unit (ICU).

Design

This was a secondary analysis.

Setting

The Phillip electronic-ICU collaborative database from 2014 to 2015.

Participants

This study included 4990 critically ill patients diagnosed with end-stage renal disease.

Primary and secondary outcome measures

The exposure of interest was serum albumin concentration. The outcome variable was cardiac arrest.

Results

A non-linear relationship was observed between serum albumin concentration and risk of cardiac arrest, with an inflection point of 3.26 g/dL after adjusting for potential confounders. The effect sizes and the CIs on the left and right sides of the inflection point were 0.88 (0.65 to 1.19) and 0.32 (0.16 to 0.64), respectively.

Conclusions

Within an albumin range of 3.26-5.6 g/dL, each 1 g/dL increase in serum levels is associated with a 68% decrease of the risk of cardiac arrest in critically ill patients with end-stage renal disease.

SUBMITTER: Zeng YQ

PROVIDER: S-EPMC8830225 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature

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Publications

Non-linear relationship between basal serum albumin concentration and cardiac arrest in critically ill patients with end-stage renal disease: a cross-sectional study.

Zeng Yong-Qin YQ Qin Zuo-An ZA Guo Zi-Wei ZW Li Bo B Yu Hai-Yan HY Chen Rui-Xue RX Tang Ying-Qian YQ Hu Ke-Jin KJ Guan Cheng-Jing CJ Yan Rui R

BMJ open 20220208 2

<h4>Objectives</h4>The aim of our study was to investigate the association between serum albumin concentration and the risk of cardiac arrest in critically ill patients with end-stage renal disease in the intensive care unit (ICU).<h4>Design</h4>This was a secondary analysis.<h4>Setting</h4>The Phillip electronic-ICU collaborative database from 2014 to 2015.<h4>Participants</h4>This study included 4990 critically ill patients diagnosed with end-stage renal disease.<h4>Primary and secondary outco ...[more]

PMID: 35135767

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Dataset Information

Non-linear relationship between basal serum albumin concentration and cardiac arrest in critically ill patients with end-stage renal disease: a cross-sectional study.

Objectives

Design

Setting

Participants

Primary and secondary outcome measures

Results

Conclusions

Publications

Non-linear relationship between basal serum albumin concentration and cardiac arrest in critically ill patients with end-stage renal disease: a cross-sectional study.

Similar Datasets

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