Dataset Information

Prioritizing outcome preferences in patients with ocular hypertension and open-angle glaucoma using best-worst scaling.

ABSTRACT: Purpose:To quantify patients' preferences for glaucoma outcomes and use this information to prioritize outcomes that are important to patients. Design:A cross-sectional study using best-worst scaling object case (BWS). Participants:Two hundred seventy-four participants newly diagnosed with ocular hypertension or mild to moderate open angle glaucoma from three private practices and one academic medical center in the United States. Methods:We designed a preference-elicitation survey based on findings from 25 semi-structured, qualitative interviews with patients with glaucoma (reported elsewhere). The survey asked participants to rate the importance of 13 glaucoma outcomes on a Likert scale as a warm-up exercise followed by completion of 13 BWS tasks. For each task, we presented participants a subset of four outcomes from the possible thirteen, and participants chose the most important and least important outcome. Outcomes included in the survey pertain to maintaining ability to perform vision-dependent activities of daily living (e.g., driving), maintaining visual function and perception (e.g., depth perception), minimizing need to take glaucoma drops, not experiencing ocular surface symptoms (e.g., red eyes, teary eyes), and having adequate control of intraocular pressure (IOP). We administered the survey online and analyzed response patterns using conditional logistic regression to determine the relative importance of different outcomes. Main outcome:Ordinal ranking of glaucoma outcomes based on preference weights. Results:Between September 1, 2017 and February 28, 2018, we invited 1035 patients to complete our survey, among whom 274 (26%) responded. Most participants were older than 65 years of age (146/274, 53%) and currently on IOP-lowering drops (179/274, 65%). Participants identified that outcomes with the largest relative importance weight were having "adequate IOP control" and ability to "drive a car during the day," and the outcomes with the smallest relative importance weights were "maintaining appearance of the eye" and "reducing the number of IOP-lowering drops". Conclusions:Determining the relative importance of glaucoma outcomes to patients can help researchers design studies that may better inform clinical and regulatory decision-making. Although IOP is an outcome that researchers often measure in glaucoma clinical trials, patients also prioritized outcomes related to the ability to perform vision-dependent activities such as driving.

SUBMITTER: Le JT

PROVIDER: S-EPMC7192342 | biostudies-literature | 2019 Nov-Dec

REPOSITORIES: biostudies-literature

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Prioritizing outcome preferences in patients with ocular hypertension and open-angle glaucoma using best-worst scaling.

Le Jimmy T JT Bicket Amanda K AK Janssen Ellen M EM Grover Davinder D Radhakrishnan Sunita S Vold Steven S Tarver Michelle E ME Eydelman Malvina M Bridges John F P JFP Li Tianjing T

Ophthalmology. Glaucoma 20190903 6

<h4>Purpose</h4>To quantify patients' preferences for glaucoma outcomes and use this information to prioritize outcomes that are important to patients.<h4>Design</h4>A cross-sectional study using best-worst scaling object case (BWS).<h4>Participants</h4>Two hundred seventy-four participants newly diagnosed with ocular hypertension or mild to moderate open angle glaucoma from three private practices and one academic medical center in the United States.<h4>Methods</h4>We designed a preference-elic ...[more]

PMID: 32355909

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Project description:Food safety is a global public health issue, which often arises from asymmetric information between consumers and suppliers. With the development of information technology in human life, building a food traceability information sharing platform is viewed as one of the best ways to overcome the trust crisis and resolve the problem of information asymmetry in China. However, among the myriad information available from the food supply chain, there is a lack of knowledge on consumer preference. Based on the best-worst scaling approach, this paper investigated consumer preferences for vegetable, pork, and dairy product traceability information. Specifically, this paper measured the relative importance that consumers place on the traceable information. The results indicate that consumers have varying priorities for information in different cases. "Pesticide/veterinary use," "picking/slaughtering date," and "fertilizer/feed use" are the most preferred traceable information for Chinese consumers in the case of vegetables, while "picking/slaughtering date" and "history of illness and taking protective measures" are the most preferred information in the case of pork. In the case of dairy products, consumers prefer "processing information," "environmental information of the origin," and "traceable tag certification information" most. The results of this study call for the direct involvement of the Chinese government in the food safety information sharing system as following. First, given consumers' diverse preferences, different types of traceable information should be recorded into the information sharing platform depending on food types. Second, the government could promote the step-by-step construction of such a platform based on the priority of consumers' preferences. Third, new technology should be applied to guarantee the reliability of traceable information. Finally, local preferences in terms of the way consumers receive and understand information should be taken into consideration.

Dataset Information

Prioritizing outcome preferences in patients with ocular hypertension and open-angle glaucoma using best-worst scaling.

Publications

Prioritizing outcome preferences in patients with ocular hypertension and open-angle glaucoma using best-worst scaling.

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