Ontology highlight
ABSTRACT:
SUBMITTER: Vallecillo-Viejo IC
PROVIDER: S-EPMC7192619 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Vallecillo-Viejo Isabel C IC Liscovitch-Brauer Noa N Diaz Quiroz Juan F JF Montiel-Gonzalez Maria F MF Nemes Sonya E SE Rangan Kavita J KJ Levinson Simon R SR Eisenberg Eli E Rosenthal Joshua J C JJC
Nucleic acids research 20200501 8
In eukaryotic cells, with the exception of the specialized genomes of mitochondria and plastids, all genetic information is sequestered within the nucleus. This arrangement imposes constraints on how the information can be tailored for different cellular regions, particularly in cells with complex morphologies like neurons. Although messenger RNAs (mRNAs), and the proteins that they encode, can be differentially sorted between cellular regions, the information itself does not change. RNA editing ...[more]