Ontology highlight
ABSTRACT:
SUBMITTER: Kotopka BJ
PROVIDER: S-EPMC7192914 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Kotopka Benjamin J BJ Smolke Christina D CD
Nature communications 20200430 1
Promoters play a central role in controlling gene regulation; however, a small set of promoters is used for most genetic construct design in the yeast Saccharomyces cerevisiae. Generating and utilizing models that accurately predict protein expression from promoter sequences would enable rapid generation of useful promoters and facilitate synthetic biology efforts in this model organism. We measure the gene expression activity of over 675,000 sequences in a constitutive promoter library and over ...[more]