Ontology highlight
ABSTRACT:
SUBMITTER: Silverman EK
PROVIDER: S-EPMC7193187 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Annual review of physiology 20191115
Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by cigarette smoking, genetic factors are also important determinants of COPD. In addition to Mendelian syndromes such as alpha-1 antitrypsin deficiency, many genomic regions that influence COPD susceptibility have been identified in genome-wide association studies. Similarly, multiple genomic regions associated with COPD-related phenotypes, such as quantitative emphysema measures, have been found. Identifying the ...[more]