Dataset Information

An analysis of the impact of Newcastle disease vaccination and husbandry practice on smallholder chicken productivity in Uganda.

ABSTRACT: A number of studies have demonstrated the clear beneficial impact that vaccinating against Newcastle disease (ND) can have on reducing the frequency and severity of ND outbreaks. Here we go one step further and analyse the additional benefits in terms of improved production that result from vaccination. Data were collected from a cross sectional survey in Uganda of 593 chicken-rearing smallholders (for the purpose of this study this was defined as a farm with fewer than 75 chickens). Consenting participants were administered a detailed questionnaire covering a range of aspects of chicken production and management. These data were subsequently analysed in a generalised linear model framework with negative binomial error structure and the total offtake over the previous 12 months (chicken sales + chicken consumption + chickens gifted) was included as the dependent variable. Different measures of flock size were tested as independent variables and the model was also offered the district of the flock, ND vaccine adoption, use of poultry housing, provision of supplementary feed and use of dewormers as potential independent variables. We also developed an analogous model for the offtake of eggs (sale and consumption). The total size of the flock (counting chickens of all ages) was the measure of flock size that had the strongest association with offtake and was a significant but weak effect with an incidence rate ratio (IRR) of 1.011 (95 % Confidence intervals (CIs) = 1.007-1.015). ND vaccine adoption had a strong significant positive effect on offtake with an IRR of 1.571 (95 % CIs = 1.363-1.808). Use of a poultry house also had a significant effect (IRR = 1.365, 95 % CIs = 1.193-1.560). In the model of egg production, the number of hens was the demographic determinant with the lowest Akaike Information Criterion (AIC) (IRR = 1.094, 95 % CIs = 1.056-1.136) and ND vaccine adoption had a strong positive effect on egg offtake (IRR = 1.801, 95 % CIs = 1.343-2.412). Vaccinating against ND has a clear beneficial impact on the productivity of the flock, and the livelihoods of smallholder farmers.

SUBMITTER: Bessell PR

PROVIDER: S-EPMC7193891 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

An analysis of the impact of Newcastle disease vaccination and husbandry practice on smallholder chicken productivity in Uganda.

Bessell Paul R PR Woolley Roy R Stevenson Stuart S Al-Riyami Lamyaa L Opondo Patrick P Lai Leslie L Gammon Neil N

Preventive veterinary medicine 20200320

A number of studies have demonstrated the clear beneficial impact that vaccinating against Newcastle disease (ND) can have on reducing the frequency and severity of ND outbreaks. Here we go one step further and analyse the additional benefits in terms of improved production that result from vaccination. Data were collected from a cross sectional survey in Uganda of 593 chicken-rearing smallholders (for the purpose of this study this was defined as a farm with fewer than 75 chickens). Consenting ...[more]

PMID: 32224372

Similar Datasets

Project description:BackgroundPoultry represent a widely held economic, nutritional, and sociocultural asset in rural communities worldwide. In a recent longitudinal study in western Kenya, the reported mean number of chickens per household was 10, with increases in flock size constrained principally by mortality. Newcastle disease virus is a major cause of chicken mortality globally and hypothesized to be responsible for a large part of mortality in smallholder flocks. Our goal was to determine the impact of routine Newcastle disease virus (NDV) vaccination on flock size and use this data to guide programs to improve small flock productivity.MethodsWe conducted a factorial randomized controlled trial in 537 households: in 254 households all chickens were vaccinated every 3 months with I-2 NDV vaccine while chickens in 283 households served as unvaccinated controls. In both arms of the trial, all chickens were treated with endo- and ecto parasiticides every 3 months. Data on household chicken numbers and reported gains and losses were collected monthly for 18 months.ResultsConsistent with prior studies, the overall flock size was small but with increases in both arms of the study over time. The mean number of chickens owned at monthly census was 13.06±0.29 in the vaccinated households versus 12.06±0.20 in the control households (p = 0.0026) with significant gains in number of chicks (p = 0.06), growers (p = 0.09), and adults (p = 0.03) in the vaccinated flocks versus the controls. Household reported gains were 4.50±0.12 total chickens per month when vaccinated versus 4.15±0.11 in the non-vaccinated controls (p = 0.03). Gains were balanced by voluntary decreases, reflecting household decision-making for sales or household consumption, which were marginally higher, but not statistically significant, in vaccinated households and by involuntary losses, including mortality and loss due to predation, which were marginally higher in control households.ConclusionQuarterly NDV vaccination and parasiticidal treatment resulted in an increase in flock size by a mean of one bird per household as compared to households where the flock received only parasiticidal treatment. While results suggest that the preventable fraction of mortality attributable to Newcastle disease is comparatively small relatively to all-cause mortality in smallholder households, there was a significant benefit to vaccination in terms of flock size. Comparison with previous flock sizes in the study households indicate a more significant benefit from the combined vaccination and parasiticidal treatment, supporting a comprehensive approach to improving flock health and improving household benefits of production in the smallholder setting.

Project description:Newcastle disease (ND) is a viral disease of poultry with global importance, responsible for the loss of a potential source of household nutrition and economic livelihood in many low-income food-deficit countries. Periodic outbreaks of this endemic disease result in high mortality amongst free-ranging chicken flocks and may serve as a disincentive for rural households to invest time or resources in poultry-keeping. Sustainable ND control can be achieved through vaccination using a thermotolerant vaccine administered via eyedrop by trained "community vaccinators". This article evaluates the uptake and outcomes of fee-for-service ND vaccination programs in eight rural villages in the semi-arid central zone of Tanzania. It represents part of an interdisciplinary program seeking to address chronic undernutrition in children through improvements to existing poultry and crop systems. Newcastle disease vaccination uptake was found to vary substantially across communities and seasons, with a significantly higher level of vaccination amongst households participating in a longitudinal study of children's growth compared with non-participating households (p = 0.009). Two multivariable model analyses were used to explore associations between vaccination and chicken numbers, allowing for clustered data and socioeconomic and cultural variation amongst the population. Results demonstrated that both (a) households that undertook ND vaccination had a significantly larger chicken flock size in the period between that vaccination campaign and the next compared with those that did not vaccinate (p = 0.018); and (b) households with larger chicken flocks at the time of vaccination were significantly more likely to participate in vaccination programs (p < 0.001). Additionally, households vaccinating in all three vaccination campaigns held over 12 months were identified to have significantly larger chicken flocks at the end of this period (p < 0.001). Opportunities to understand causality and complexity through quantitative analyses are limited, and there is a role for qualitative approaches to explore decisions made by poultry-keeping households and the motivations, challenges and priorities of community vaccinators. Evidence of a bi-directional relationship, however, whereby vaccination leads to greater chicken numbers, and larger flocks are more likely to be vaccinated, offers useful insights into the efficacy of fee-for-service animal health programs. This article concludes that attention should be focused on ways of supporting the participation of vulnerable households in ND vaccination campaigns, and encouraging regular vaccination throughout the year, as a pathway to strengthen food security, promote resilience and contribute to improved human nutrition.

Project description:The Newcastle disease virus (NDV) is the deadliest chicken pathogen in low-input village poultry, and selecting for NDV resistance has been recommended as a sustainable strategy in backyard poultry production systems. However, selecting for disease resistance needs precision data from either a big population sample size or on many generations with good pedigree records for effective prediction of heritability (h2 ) and breeding values of the foundation stock. Such conditions are almost impossible to meet in low-input backyard production systems. This study aimed at proposing a realistic method for estimating the heritability of the immune response to vaccination and survival of NDV infection in village poultry production to inform a breeding strategy for ND resistance in Cameroon. A 1 and 3% selection intensity of cocks and hens for higher antibody (ab) response (ABR) to vaccination followed by progeny selection of chickens who survived an experimental NDV infection was conducted from an initial population of 1,702 chickens. The selection induced an increase of 1012.47units/ml (p<0.01) of the NDV antibody of the progeny as well as an effective survival rate (ESR) increase of 11.75%. Three methods were used to estimate the heritability ( h2 ) of NDV antibody response to vaccination. h2 was low irrespective of the method with estimates of 0.2227, 0.2442, and 0.2839 for the breeder's equation method, the graphical method, and the full-sib/half-sib nested design, respectively. The mortality rate of infected chickens was high (86%). The antibody response to selection was not influenced by sex and genetic type even though the opposite was observed (p<0.05) for the ESR to NDV infection with naked neck chickens recording an ESR of 14% against 2.25% for the normal feather type. A very low heritability (0.0891) was observed for the survival against NDV infection. We confirm the evidence of disease resistance and the effect of selection for antibody response to vaccination on the improvement of the survival against NDV disease. Although the full sib/half sib nested design is more appropriate in case of availability of pedigree information, the direct methods are still useful in case of unavailability of full pedigree information. It is recommended that gene expression analysis should be prioritized for disease-resistance assessment and selection of native breeds of poultry.

Dataset Information

An analysis of the impact of Newcastle disease vaccination and husbandry practice on smallholder chicken productivity in Uganda.

Publications

An analysis of the impact of Newcastle disease vaccination and husbandry practice on smallholder chicken productivity in Uganda.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets