Ontology highlight
ABSTRACT:
SUBMITTER: Okazaki S
PROVIDER: S-EPMC7198548 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Okazaki Satoshi S Numata Shusuke S Otsuka Ikuo I Horai Tadasu T Kinoshita Makoto M Sora Ichiro I Ohmori Tetsuro T Hishimoto Akitoyo A
Translational psychiatry 20200504 1
There is high mortality among patients with bipolar disorder (BD). Studies have reported accelerated biological aging in patients with BD. Recently, Horvath and Hannum et al. independently developed DNA methylation (DNAm) profiles as "epigenetic clocks," which are the most accurate biological age estimate. This led to the development of two accomplished measures of epigenetic age acceleration (EAA) using blood samples, namely, intrinsic and extrinsic EAA (IEAA and EEAA, respectively). IEAA, whic ...[more]