Ontology highlight
ABSTRACT:
SUBMITTER: Merad M
PROVIDER: S-EPMC7201395 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Nature reviews. Immunology 20200506 6
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease severity and death in infected patients. Macrophages are a population of innate immune cells that sense and respond to microbial threats by producing inflammatory molecules that eliminate pathogens and promote tissue repair. However, a dysregulated macrophage response can ...[more]