Effect of Ki-67 Expression Levels and Histological Grade on Breast Cancer Early Relapse in Patients with Different Immunohistochemical-based Subtypes.
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ABSTRACT:
SUBMITTER: Liang Q
PROVIDER: S-EPMC7203155 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Effect of Ki-67 Expression Levels and Histological Grade on Breast Cancer Early Relapse in Patients with Different Immunohistochemical-based Subtypes.
Liang Qin Q Ma Ding D Gao Run-Fang RF Yu Ke-Da KD
Scientific reports 20200506 1
This retrospective analysis evaluated the interaction between Ki-67 and histological grade and their prognostic role in different breast cancer subtypes. In total, 2,573 breast cancer patients underwent surgery, and their histological grade and Ki-67 values were evaluated by breast pathologists. The median Ki-67 index was 15%, which was used as the cut-off for low/high Ki-67 expression. Recurrence-free survival (RFS) was calculated and compared, and the results indicated that Ki-67 expression wa ...[more]
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