Ontology highlight
ABSTRACT:
SUBMITTER: Monteiro MB
PROVIDER: S-EPMC7204506 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Monteiro Maria Beatriz MB Pelaes Tatiana S TS Santos-Bezerra Daniele P DP Thieme Karina K Lerario Antonio M AM Oba-Shinjo Sueli M SM Machado Ubiratan F UF Passarelli Marisa M Marie Suely K N SKN Corrêa-Giannella Maria Lúcia ML
Frontiers in endocrinology 20200430
<b>Introduction:</b> Using a discovery/validation approach we investigated associations between a panel of genes selected from a transcriptomic study and the estimated glomerular filtration rate (eGFR) decline across time in a cohort of type 1 diabetes (T1D) patients. <b>Experimental:</b> Urinary sediment transcriptomic was performed to select highly modulated genes in T1D patients with rapid eGFR decline (decliners) vs. patients with stable eGFR (non-decliners). The selected genes were validate ...[more]