Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Lagunas K
PROVIDER: S-EPMC7205869 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Martínez-Lagunas Kristel K Yamaguchi Yoshifumi Y Becker Cora C Geisen Caroline C DeRuiter Marco C MC Miura Masayuki M Fleischmann Bernd K BK Hesse Michael M
Cell death and differentiation 20190930 4
Despite the great progress on the cell biology of programmed cell death (PCD), its incidence and exact time course during embryonic and particular heart development are still unclear. This is also due to the lack of models enabling to directly identify and monitor PCD cells at different time points in vivo. Herein we report generation of transgenic murine embryonic stem cell and mouse models expressing secreted Annexin V-YFP under control of the CAG promoter. This enables to visualize and quanti ...[more]