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ABSTRACT: Objective
To define the epidemiological profile and the main determinants of morbidity and mortality in noncardiac high surgical risk patients in Brazil.Methods
This was a prospective, observational and multicenter study. All noncardiac surgical patients admitted to intensive care units, i.e., those considered high risk, within a 1-month period were evaluated and monitored daily for a maximum of 7 days in the intensive care unit to determine complications. The 28-day postoperative, intensive care unit and hospital mortality rates were evaluated.Results
Twenty-nine intensive care units participated in the study. Surgeries were performed in 25,500 patients, of whom 904 (3.5%) were high-risk (95% confidence interval - 95%CI 3.3% - 3.8%) and were included in the study. Of the participating patients, 48.3% were from private intensive care units, and 51.7% were from public intensive care units. The length of stay in the intensive care unit was 2.0 (1.0 - 4.0) days, and the length of hospital stay was 9.5 (5.4 - 18.6) days. The complication rate was 29.9% (95%CI 26.4 - 33.7), and the 28-day postoperative mortality rate was 9.6% (95%CI 7.4 - 12.1). The independent risk factors for complications were the Simplified Acute Physiology Score 3 (SAPS 3; odds ratio - OR = 1.02; 95%CI 1.01 - 1.03) and Sequential Organ Failure Assessment Score (SOFA) on admission to the intensive care unit (OR = 1.17; 95%CI 1.09 - 1.25), surgical time (OR = 1.001, 95%CI 1.000 - 1.002) and emergency surgeries (OR = 1.93, 95%CI, 1.10 - 3.38). In addition, there were associations with 28-day mortality (OR = 1.032; 95%CI 1.011 - 1.052), SAPS 3 (OR = 1.041; 95%CI 1.107 - 1.279), SOFA (OR = 1.175, 95%CI 1.069 - 1.292) and emergency surgeries (OR = 2.509; 95%CI 1.040 - 6.051).Conclusion
Higher prognostic scores, elderly patients, longer surgical times and emergency surgeries were strongly associated with higher 28-day mortality and more complications during the intensive care unit stay.
SUBMITTER: Silva Junior JM
PROVIDER: S-EPMC7206944 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Silva Júnior João Manoel JM Chaves Renato Carneiro de Freitas RCF Corrêa Thiago Domingos TD Assunção Murillo Santucci Cesar de MSC Katayama Henrique Tadashi HT Bosso Fabio Eduardo FE Amendola Cristina Prata CP Serpa Neto Ary A Malbouisson Luiz Marcelo Sá LMS Oliveira Neymar Elias de NE Veiga Viviane Cordeiro VC Rojas Salomón Soriano Ordinola SSO Postalli Natalia Fioravante NF Alvarisa Thais Kawagoe TK Lucena Bruno Melo Nobrega de BMN Oliveira Raphael Augusto Gomes de RAG Sanches Luciana Coelho LC Silva Ulysses Vasconcellos de Andrade E UVAE Nassar Junior Antonio Paulo AP
Revista Brasileira de terapia intensiva 20200301 1
<h4>Objective</h4>To define the epidemiological profile and the main determinants of morbidity and mortality in noncardiac high surgical risk patients in Brazil.<h4>Methods</h4>This was a prospective, observational and multicenter study. All noncardiac surgical patients admitted to intensive care units, i.e., those considered high risk, within a 1-month period were evaluated and monitored daily for a maximum of 7 days in the intensive care unit to determine complications. The 28-day postoperativ ...[more]