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Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from the SEARCH study.


ABSTRACT:

SUBMITTER: Koss CA 

PROVIDER: S-EPMC7208546 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Uptake, engagement, and adherence to pre-exposure prophylaxis offered after population HIV testing in rural Kenya and Uganda: 72-week interim analysis of observational data from the SEARCH study.

Koss Catherine A CA   Charlebois Edwin D ED   Ayieko James J   Kwarisiima Dalsone D   Kabami Jane J   Balzer Laura B LB   Atukunda Mucunguzi M   Mwangwa Florence F   Peng James J   Mwinike Yusuf Y   Owaraganise Asiphas A   Chamie Gabriel G   Jain Vivek V   Sang Norton N   Olilo Winter W   Brown Lillian B LB   Marquez Carina C   Zhang Kevin K   Ruel Theodore D TD   Camlin Carol S CS   Rooney James F JF   Black Douglas D   Clark Tamara D TD   Gandhi Monica M   Cohen Craig R CR   Bukusi Elizabeth A EA   Petersen Maya L ML   Kamya Moses R MR   Havlir Diane V DV  

The lancet. HIV 20200219 4


<h4>Background</h4>Optimal strategies for pre-exposure prophylaxis (PrEP) engagement in generalised HIV epidemics are unknown. We aimed to assess PrEP uptake and engagement after population-level HIV testing and universal PrEP access to characterise gaps in the PrEP cascade in rural Kenya and Uganda.<h4>Methods</h4>We did a 72-week interim analysis of observational data from the ongoing SEARCH (Sustainable East Africa Research in Community Health) study. Following community sensitisation and PrE  ...[more]

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