Targeting the PI3K/AKT/mTOR/NF?B Axis in Ovarian Cancer.
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ABSTRACT:
SUBMITTER: Ghoneum A
PROVIDER: S-EPMC7213295 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Targeting the PI3K/AKT/mTOR/NFκB Axis in Ovarian Cancer.
Ghoneum Alia A Abdulfattah Ammar Yasser AY Said Neveen N
Journal of cellular immunology 20200101 2
Ovarian cancer stands as the most lethal gynecologic malignancy and remains the fifth most common gynecologic cancer. Poor prognosis and low five-year survival rate are attributed to nonspecific symptoms at early phases along with a lack of effective treatment at advanced stages. It is thus paramount, that ovarian carcinoma be viewed through several lenses in order to gain a thorough comprehension of its molecular pathogenesis, epidemiology, histological subtypes, hereditary factors, diagnostic ...[more]
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