Caenorhabditis elegans processes sensory information to choose between freeloading and self-defense strategies.
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ABSTRACT:
SUBMITTER: Schiffer JA
PROVIDER: S-EPMC7213980 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
<i>Caenorhabditis elegans</i> processes sensory information to choose between freeloading and self-defense strategies.
Schiffer Jodie A JA Servello Francesco A FA Heath William R WR Amrit Francis Raj Gandhi FRG Stumbur Stephanie V SV Eder Matthias M Martin Olivier Mf OM Johnsen Sean B SB Stanley Julian A JA Tam Hannah H Brennan Sarah J SJ McGowan Natalie G NG Vogelaar Abigail L AL Xu Yuyan Y Serkin William T WT Ghazi Arjumand A Stroustrup Nicholas N Apfeld Javier J
eLife 20200505
Hydrogen peroxide is the preeminent chemical weapon that organisms use for combat. Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage, but whether similar defenses might be coordinated across cells in animals remains poorly understood. Here, we identify a neuronal circuit in the nematode <i>Caenorhabditis elegans</i> that processes information perceived by two sensory neurons to control the induction of hydrogen peroxide defenses in the organism. We found t ...[more]
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