Ontology highlight
ABSTRACT:
SUBMITTER: Saber A
PROVIDER: S-EPMC7214581 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Saber Ali A Liu Bin B Ebrahimi Pirooz P Haisma Hidde J HJ
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20190121 1
<h4>Objectives</h4>In this review, we focus on the application of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated nuclease 9 (Cas9), as a powerful genome editing system, in the identification of resistance mechanisms and in overcoming drug resistance in the most frequent solid tumors.<h4>Data acquisition</h4>Data were collected by conducting systematic searching of scientific English literature using specific keywords such as "cancer", "CRISPR" and related co ...[more]