Ontology highlight
ABSTRACT:
SUBMITTER: Forsare C
PROVIDER: S-EPMC7215368 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Forsare Carina C Bendahl Pär-Ola PO Moberg Eric E Levin Tykjær Jørgensen Charlotte C Jansson Sara S Larsson Anna-Maria AM Aaltonen Kristina K Rydén Lisa L
International journal of molecular sciences 20200420 8
<h4>Background</h4>The estrogen receptor (ER) can change expression between primary tumor (PT) and distant metastasis (DM) in breast cancer. A tissue biopsy reflects a momentary state at one location, whereas circulating tumor cells (CTCs) reflect real-time tumor progression. We evaluated ER-status during tumor progression from PT to DM and CTCs, and related the ER-status of CTCs to prognosis.<h4>Methods</h4>In a study of metastatic breast cancer, blood was collected at different timepoints. Aft ...[more]