Ontology highlight
ABSTRACT:
SUBMITTER: Du M
PROVIDER: S-EPMC7216329 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Du Mengyi M Hari Parameswaran P Hu Yu Y Mei Heng H
Biomarker research 20200511
The development of chimeric antigen receptor (CAR) T cell immunotherapy has achieved promising results, both in clinical studies and in commercial products for patients with hematologic malignancies. Despite high remission rates of CAR-T cell therapy in previously untreatable, refractory and/or relapsed patients, several challenges in CAR-T therapy remain to be overcome, especially in integrating such therapies into personalized disease management approaches. Given the unique characteristics of ...[more]