Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain.

ABSTRACT: BACKGROUND:Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD. METHODS:From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1?±?11.3?years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3?L) and the Hospital Anxiety and Depression Scale. RESULTS:Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2?±?8.8, 43.3?±?9.1, 46.2?±?9.0, 46.4?±?11.4, respectively, all age and gender-adjusted p?

SUBMITTER: Rieckmann N 

PROVIDER: S-EPMC7222590 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature