Ontology highlight
ABSTRACT:
SUBMITTER: Gao DW
PROVIDER: S-EPMC7227802 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Nature catalysis 20191202 1
Enantioenriched <i>α</i>-aminoboronic acids play a unique role in medicinal chemistry and have emerged as privileged pharmacophores in proteasome inhibitors. Additionally, they represent synthetically useful chiral building blocks in organic synthesis. Recently, CuH-catalyzed asymmetric alkene hydrofunctionalization has become a powerful tool to construct stereogenic carbon centers. In contrast, applying CuH cascade catalysis to achieve reductive 1,1-difunctionalization of alkynes remains an imp ...[more]