Ontology highlight
ABSTRACT:
SUBMITTER: Latacz M
PROVIDER: S-EPMC7230796 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Nutrients 20200403 4
Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide. Intestinal cells are <i>CYP27B1</i> gene expression sites and, as a consequence, they are capable of converting pro-vitamin D into the active paracrine and autocrine forms. It was demonstrated that rs10877012 polymorphism in the <i>CYP27B1</i> gene influenced the circulating vitamin D level. This provided a rationale for determining the role that this polymorphism plays in the risk of developing colon cancer. In this ...[more]