Ontology highlight
ABSTRACT:
SUBMITTER: Gao F
PROVIDER: S-EPMC7232748 | biostudies-literature | 2003 Oct
REPOSITORIES: biostudies-literature
Gao Feng F Ou Hong-Yu HY Chen Ling-Ling LL Zheng Wen-Xin WX Zhang Chun-Ting CT
FEBS letters 20031001 3
Recently, we have developed a coronavirus-specific gene-finding system, ZCURVE_CoV 1.0. In this paper, the system is further improved by taking the prediction of cleavage sites of viral proteinases in polyproteins into account. The cleavage sites of the 3C-like proteinase and papain-like proteinase are highly conserved. Based on the method of traditional positional weight matrix trained by the peptides around cleavage sites, the present method also sufficiently considers the length conservation ...[more]