Defining the oral microbiome by whole-genome sequencing and resistome analysis: the complexity of the healthy picture.

ABSTRACT:

Background

The microbiome of the oral cavity is the second-largest and diverse microbiota after the gut, harboring over 700 species of bacteria and including also fungi, viruses, and protozoa. With its diverse niches, the oral cavity is a very complex environment, where different microbes preferentially colonize different habitats. Recent data indicate that the oral microbiome has essential functions in maintaining oral and systemic health, and the emergence of 16S rRNA gene next-generation sequencing (NGS) has greatly contributed to revealing the complexity of its bacterial component. However, a detailed site-specific map of oral microorganisms (including also eukaryotes and viruses) and their relative abundance is still missing. Here, we aimed to obtain a comprehensive view of th

SUBMITTER: Caselli E 

PROVIDER: S-EPMC7236360 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature