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Sex Differences in Comorbidity and Frailty in Europe.


ABSTRACT: OBJECTIVES:To examine sex differences in prevalent comorbidity and frailty across age and European regions. METHODS:This is a cross-sectional study based on 113,299 Europeans aged 50+ participating in the Survey of Health, Ageing and Retirement in Europe from 2004-2005 to 2015. Sex differences in the Comorbidity Index and the Frailty Phenotype were investigated using ordinal logistic regressions. RESULTS:European women had generally higher odds of prevalent comorbidity (OR 1.11, 95% CI 1.07-1.15) and frailty (OR 1.56, 95% CI 1.51-1.62). Sex differences increased with advancing age. No overall sex difference in comorbidity was found in Western Europe, but women had more comorbidity than men in Eastern (OR 1.30, 95% CI 1.18-1.44), Southern (OR 1.23, 95% CI 1.15-1.30), and Northern (OR 1.08, 95% CI 1.01-1.16) Europe. Women were frailer than men in all regions, with the largest sex difference in Southern Europe (OR 1.84, 95% CI 1.72-1.96). CONCLUSIONS:European women are frailer and have slightly more comorbidity than European men lending support for the male-female health survival paradox.

SUBMITTER: Ahrenfeldt LJ 

PROVIDER: S-EPMC7237816 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Sex Differences in Comorbidity and Frailty in Europe.

Ahrenfeldt Linda Juel LJ   Möller Sören S   Thinggaard Mikael M   Christensen Kaare K   Lindahl-Jacobsen Rune R  

International journal of public health 20190624 7


<h4>Objectives</h4>To examine sex differences in prevalent comorbidity and frailty across age and European regions.<h4>Methods</h4>This is a cross-sectional study based on 113,299 Europeans aged 50+ participating in the Survey of Health, Ageing and Retirement in Europe from 2004-2005 to 2015. Sex differences in the Comorbidity Index and the Frailty Phenotype were investigated using ordinal logistic regressions.<h4>Results</h4>European women had generally higher odds of prevalent comorbidity (OR  ...[more]

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