Unknown

Dataset Information

0

Ethylicin Prevents Potato Late Blight by Disrupting Protein Biosynthesis of Phytophthora infestans.

ABSTRACT: Phytophthora infestans, the causal agent of potato late blight, triggered the devastating Great Irish Famine that lasted from 1845 to 1852. Today, it is still the greatest threat to the potato yield. Ethylicin is a broad-spectrum biomimetic-fungicide. However, its application in the control of Phytophthora infestans is still unknown. In this study, we investigated the effects of ethylicin on Phytophthora infestans. We found that ethylicin inhibited the mycelial growth, sporulation capacity, spore germination and virulence of Phytophthora infestans. Furthermore, the integrated analysis of proteomics and metabolomics indicates that ethylicin may inhibit peptide or protein biosynthesis by suppressing both the ribosomal function and amino acid metabolism, causing an inhibitory effect on Phytophthora infestans. These observations indicate that ethylicin may be an anti-oomycete agent that can be used to control Phytophthora infestans.

SUBMITTER: Zhang S 

PROVIDER: S-EPMC7238019 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Ethylicin Prevents Potato Late Blight by Disrupting Protein Biosynthesis of <i>Phytophthora infestans</i>.

Zhang Shumin S   Zhang Meiquan M   Khalid A Rehman AR   Li Linxuan L   Chen Yang Y   Dong Pan P   Wang Hanyan H   Ren Maozhi M  

Pathogens (Basel, Switzerland) 20200419 4

<i>Phytophthora infestans</i>, the causal agent of potato late blight, triggered the devastating Great Irish Famine that lasted from 1845 to 1852. Today, it is still the greatest threat to the potato yield. Ethylicin is a broad-spectrum biomimetic-fungicide. However, its application in the control of <i>Phytophthora infestans</i> is still unknown. In this study, we investigated the effects of ethylicin on <i>Phytophthora infestans</i>. We found that ethylicin inhibited the mycelial growth, sporu  ...[more]

Similar Datasets

Unknown Plant-mediated gene silencing restricts growth of the potato late blight pathogen Phytophthora infestans.
| S-EPMC4986879 | biostudies-other
Unknown Melatonin Attenuates Potato Late Blight by Disrupting Cell Growth, Stress Tolerance, Fungicide Susceptibility and Homeostasis of Gene Expression in Phytophthora infestans.
| S-EPMC5702310 | biostudies-literature
Unknown Profiling the secretome and extracellular proteome of the potato late blight pathogen Phytophthora infestans.
| S-EPMC4125740 | biostudies-literature
Unknown Contrasting Potato Foliage and Tuber Defense Mechanisms against the Late Blight Pathogen Phytophthora infestans.
| S-EPMC4956046 | biostudies-literature
Unknown EIN2-mediated signaling is involved in pre-invasion defense in Nicotiana benthamiana against potato late blight pathogen, Phytophthora infestans.
| S-EPMC5437821 | biostudies-other
Unknown Diverse mechanisms shape the evolution of virulence factors in the potato late blight pathogen Phytophthora infestans sampled from China.
| S-EPMC4872137 | biostudies-other
Unknown Correction to: Patil et al., Complete mitogenome mapping of potato late blight pathogen, Phytophthora infestans A2 mating type
| S-EPMC7687609 | biostudies-literature
Unknown Complete mitogenome mapping of potato late blight pathogen, <i>Phytophthora infestans</i> A<sub>2</sub> mating type.
| S-EPMC7800244 | biostudies-literature
Proteomics Profiling the secretome and extracellular proteome of the potato late blight pathogen Phytophthora infestans
2016-07-09 | PXD000802 | Pride
Unknown Comparative transcriptome profiling of potato cultivars infected by late blight pathogen Phytophthora infestans: Diversity of quantitative and qualitative responses.
| S-EPMC10548088 | biostudies-literature