Ontology highlight
ABSTRACT:
SUBMITTER: Yu J
PROVIDER: S-EPMC7238648 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Yu Jifeng J Jiang Peter Y Z PYZ Sun Hao H Zhang Xia X Jiang Zhongxing Z Li Yingmei Y Song Yongping Y
Biomarker research 20200520
Acute myeloid leukemia (AML) is a clonal malignancy characterized by genetic heterogeneity due to recurrent gene mutations. Treatment with cytotoxic chemotherapy has been the standard of care for more than half of a century. Although much progress has been made toward improving treatment related mortality rate in the past few decades, long term overall survival has stagnated. Exciting developments of gene mutation-targeted therapeutic agents are now changing the landscape in AML treatment. New a ...[more]