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Elevated blood eosinophils in acute COPD exacerbations: better short- and long-term prognosis.


ABSTRACT: Background: Elevated eosinophils in COPD is recognized as a potential risk factor for exacerbations, but the prognostic role of elevated eosinophils during exacerbations of COPD is unclear. We investigated short-term and long-term outcomes in patients with exacerbations of eosinophilic phenotype, compared with patients with low blood eosinophils. Methods: A single-centre retrospective study of all patients admitted for a COPD exacerbation to Bispebjerg University Hospital in 2010-2011 was established by linking inpatient data with national patient and prescription registries, with a three-year follow-up period. Elevated eosinophils were defined as a blood eosinophil level at admission of ≥0.30 × 109 cells/L. Results: A total of 811 patients were included; 13

SUBMITTER: Jabarkhil A 

PROVIDER: S-EPMC7241534 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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