Ontology highlight
ABSTRACT:
SUBMITTER: Khan S
PROVIDER: S-EPMC7243349 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Khan Saad S Chan Yi Tao YT Revelo Xavier S XS Winer Daniel A DA
Frontiers in endocrinology 20200515
Obesity and aging represent major health burdens to the global adult population. Both conditions promote the development of associated metabolic diseases such as insulin resistance. The visceral adipose tissue (VAT) is a site that becomes dysfunctional during obesity and aging, and plays a significant role during their pathophysiology. The changes in obese and aging VAT are now recognized to be partly driven by a chronic local inflammatory state, characterized by immune cells that typically adop ...[more]