Ontology highlight
ABSTRACT:
SUBMITTER: Pitoulis FG
PROVIDER: S-EPMC7246333 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Pitoulis Fotios G FG Hasan Waseem W Papadaki Mary M Clavere Nicolas G NG Perbellini Filippo F Harding Sian E SE Kirk Jonathan A JA Boateng Samuel Y SY de Tombe Pieter P PP Terracciano Cesare M CM
Journal of molecular and cellular cardiology 20200319
Determining transmural mechanical properties in the heart provides a foundation to understand physiological and pathophysiological cardiac mechanics. Although work on mechanical characterisation has begun in isolated cells and permeabilised samples, the mechanical profile of living individual cardiac layers has not been examined. Myocardial slices are 300 μm-thin sections of heart tissue with preserved cellular stoichiometry, extracellular matrix, and structural architecture. This allows for car ...[more]