Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC7246536 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Xu Xingbo X Hulshoff Melanie S MS Tan Xiaoying X Zeisberg Michael M Zeisberg Elisabeth M EM
International journal of molecular sciences 20200425 9
The field of genome editing started with the discovery of meganucleases (e.g., the LAGLIDADG family of homing endonucleases) in yeast. After the discovery of transcription activator-like effector nucleases and zinc finger nucleases, the recently discovered clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated proteins (Cas) system has opened a new window of applications in the field of gene editing. Here, we review different Cas proteins and their corresponding fea ...[more]