Ontology highlight
ABSTRACT:
SUBMITTER: Wen W
PROVIDER: S-EPMC7247424 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Wen Wen W Song Shanshan S Han Yuchun Y Chen Haibin H Liu Xiangzhen X Qian Qijun Q
International journal of molecular sciences 20200426 9
As non-viral transgenic vectors, the <i>piggyBac</i> transposon system represents an attractive tool for gene delivery to achieve a long-term gene expression in immunotherapy applications due to its large cargo capacity, its lack of a trace of transposon and of genotoxic potential, and its highly engineered structure. However, further improvements in transpose activity are required for industrialization and clinical applications. Herein, we established a one-plasmid effective screening system an ...[more]