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Low-frequency noise induced by cation exchange fluctuation on the wall of silicon nitride nanopore.


ABSTRACT: Nanopore-based biosensors have attracted attention as highly sensitive microscopes for detecting single molecules in aqueous solutions. However, the ionic current noise through a nanopore degrades the measurement accuracy. In this study, the magnitude of the low-frequency noise in the ionic current through a silicon nitride nanopore was found to change depending on the metal ion species in the aqueous solution. The order of the low-frequency noise magnitudes of the alkali metal ionic current was consistent with the order of the adsorption affinities of the metal ions for the silanol surface of the nanopore (Li 2 aqueous solution with a CsCl aqueous solution, indicating that Ca ions continued being adsorbed onto silanol groups even after removing the aqueous solution.

SUBMITTER: Matsui K 

PROVIDER: S-EPMC7250840 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Low-frequency noise induced by cation exchange fluctuation on the wall of silicon nitride nanopore.

Matsui Kazuma K   Goto Yusuke Y   Yanagi Itaru I   Akahori Rena R   Fujioka Michiru M   Ishida Takeshi T   Yokoi Takahide T   Nakagawa Tatsuo T   Takeda Ken-Ichi KI  

Scientific reports 20200526 1


Nanopore-based biosensors have attracted attention as highly sensitive microscopes for detecting single molecules in aqueous solutions. However, the ionic current noise through a nanopore degrades the measurement accuracy. In this study, the magnitude of the low-frequency noise in the ionic current through a silicon nitride nanopore was found to change depending on the metal ion species in the aqueous solution. The order of the low-frequency noise magnitudes of the alkali metal ionic current was  ...[more]

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