Ontology highlight
ABSTRACT:
SUBMITTER: Larson-Casey JL
PROVIDER: S-EPMC7251238 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Larson-Casey Jennifer L JL He Chao C Carter A Brent AB
Redox biology 20200108
Mechanisms underlying the pathogenesis of pulmonary fibrosis remain incompletely understood. Emerging evidence suggests changes in mitochondrial quality control are a critical determinant in many lung diseases, including chronic obstructive pulmonary disease, asthma, pulmonary hypertension, acute lung injury, lung cancer, and in the susceptibility to pulmonary fibrosis. Once thought of as the kidney-bean shaped powerhouses of the cell, mitochondria are now known to form interconnected networks t ...[more]