Urinary activated leukocyte cell adhesion molecule as a novel biomarker of lupus nephritis histology.
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ABSTRACT:
SUBMITTER: Ding H
PROVIDER: S-EPMC7251704 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Urinary activated leukocyte cell adhesion molecule as a novel biomarker of lupus nephritis histology.
Ding Huihua H Lin Cheng C Cai Jingyi J Guo Qiang Q Dai Min M Mohan Chandra C Shen Nan N
Arthritis research & therapy 20200527 1
<h4>Background</h4>Lupus nephritis (LN) is one of the most severe complications of SLE patients. We aim to validate urinary ALCAM as a biomarker in predicting renal disease histpathology in a Chinese lupus cohort.<h4>Methods</h4>In this cross-sectional study, a total of 256 patients and controls were recruited. Urinary levels of ALCAM were determined by ELISA. Renal histopathology was reviewed by an experienced renal pathologist.<h4>Results</h4>Urinary ALCAM levels were significantly increased i ...[more]
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