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The Interface between Keratin Structurotype and Human Disease.


ABSTRACT: In this issue of Structure, Coulombe and coworkers (Lee et al., 2020) present the crystal structure of the keratin 5/14 2B heterodimeric complex containing the keratin 14 substitution C367A. The authors identify a 2B-2B contact interface important to the elongation of mature keratin 5/14 filaments.

SUBMITTER: Eldirany SA 

PROVIDER: S-EPMC7252399 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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The Interface between Keratin Structurotype and Human Disease.

Eldirany Sherif A SA   Ho Minh M   Bunick Christopher G CG  

Structure (London, England : 1993) 20200301 3


In this issue of Structure, Coulombe and coworkers (Lee et al., 2020) present the crystal structure of the keratin 5/14 2B heterodimeric complex containing the keratin 14 substitution C367A. The authors identify a 2B-2B contact interface important to the elongation of mature keratin 5/14 filaments. ...[more]

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