Ontology highlight
ABSTRACT:
SUBMITTER: Huang W
PROVIDER: S-EPMC7255376 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Huang Wenhui W Qian Tingting T Cheng Zhiheng Z Zeng Tiansheng T Si Chaozeng C Liu Chaojun C Deng Cong C Ye Xu X Liu Yan Y Cui Longzhen L Fu Lin L
Journal of Cancer 20200518 15
Acute myeloid leukemia (AML) is a clonal and heterogeneous disease characterized by proliferation of immature myeloid cells, with impaired differentiation and maturation. Spinster homolog (SPNS) is a widely distributed transmembrane transporter, which assists sphingolipids in playing their roles through the cell membrane. However, the expression and clinical implication of the <i>SPNS</i> family has not been investigated in AML. From the Cancer Genome Atlas database, a total of 155 AML patients ...[more]