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Disability trajectories and mortality in older adults with different cognitive and physical profiles.


ABSTRACT: BACKGROUND:Cognitive and physical deficits independently raise the risk for negative events in older adults. Less is known about whether their co-occurrence constitutes a distinct risk profile. This study quantifies the association between cognitive impairment, no dementia (CIND), slow walking speed (WS) and their combination and disability and mortality. METHODS:We examined 2546 dementia-free people aged ??60 years, part of the Swedish National study on Aging and Care in Kungsholmen (SNAC-K) up to 12 years. The following four profiles were created: (1) healthy profile; (2) isolated CIND (scoring 1.5 SD below age-specific means on at least one cognitive domain); (3) isolated slow WS (

SUBMITTER: Grande G 

PROVIDER: S-EPMC7260142 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Disability trajectories and mortality in older adults with different cognitive and physical profiles.

Grande Giulia G   Vetrano Davide L DL   Fratiglioni Laura L   Marseglia Anna A   Vanacore Nicola N   Laukka Erika Jonsson EJ   Welmer Anna-Karin AK   Rizzuto Debora D  

Aging clinical and experimental research 20190830 6


<h4>Background</h4>Cognitive and physical deficits independently raise the risk for negative events in older adults. Less is known about whether their co-occurrence constitutes a distinct risk profile. This study quantifies the association between cognitive impairment, no dementia (CIND), slow walking speed (WS) and their combination and disability and mortality.<h4>Methods</h4>We examined 2546 dementia-free people aged ≥ 60 years, part of the Swedish National study on Aging and Care in Kungshol  ...[more]

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