Ontology highlight
ABSTRACT:
SUBMITTER: Dieterle ME
PROVIDER: S-EPMC7263493 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
bioRxiv : the preprint server for biology 20200520
There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid SARS-CoV-2 countermeasure development is contingent on the availability of robust, scalable, and readily deployable surrogate viral assays to screen antiviral humoral responses, and define correlates of immune protection, and to down-select candidate antivirals. Here, we describe a highly infectious recombinant vesicular stomatitis virus bearing the SARS-CoV-2 spike glycoprotein S as its sole entry glycopr ...[more]