Ontology highlight
ABSTRACT:
SUBMITTER: Dieterle ME
PROVIDER: S-EPMC7332447 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Cell host & microbe 20200703 3
There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid SARS-CoV-2 countermeasure development is contingent on the availability of robust, scalable, and readily deployable surrogate viral assays to screen antiviral humoral responses, define correlates of immune protection, and down-select candidate antivirals. Here, we generate a highly infectious recombinant vesicular stomatitis virus (VSV) bearing the SARS-CoV-2 spike glycoprotein S as its sole entry glycopro ...[more]