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Dendritic Hydrogel Bioink for 3D Printing of Bacterial Microhabitat.

ABSTRACT: A glucose-modified dendritic hydrogel is used as a bioink for bacterial encapsulation. This biocompatible hydrogel is a potentially suitable alternative to conventional alginate hydrogel for bacterial encapsulation, as it readily forms gel in the presence of Na+ or K+ ions without any additional stimuli such as pH, temperature, sonication, or the presence of divalent metal ions. We created a bacterial microhabitat by adding the gelator to phosphate-buffered saline containing live bacteria at physiological pH and using an additive three-dimensional (3D) printing technique. The bacteria remained viable and metabolically active within the 3D printed bacterial microhabitat, as shown with confocal laser scanning microscopy (CLSM) and scanning electrochemical microscopy (SECM).

SUBMITTER: Sheet PS

PROVIDER: S-EPMC7266169 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Dendritic Hydrogel Bioink for 3D Printing of Bacterial Microhabitat.

Sheet Partha S PS Koley Dipankar D

ACS applied bio materials 20191115 12

A glucose-modified dendritic hydrogel is used as a bioink for bacterial encapsulation. This biocompatible hydrogel is a potentially suitable alternative to conventional alginate hydrogel for bacterial encapsulation, as it readily forms gel in the presence of Na<sup>+</sup> or K<sup>+</sup> ions without any additional stimuli such as pH, temperature, sonication, or the presence of divalent metal ions. We created a bacterial microhabitat by adding the gelator to phosphate-buffered saline containin ...[more]

PMID: 32490360

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