Long-term dietary intervention reveals resilience of the gut microbiota despite changes in diet and weight.

ABSTRACT:

Background

With the rising rates of obesity and associated metabolic disorders, there is a growing need for effective long-term weight-loss strategies, coupled with an understanding of how they interface with human physiology. Interest is growing in the potential role of gut microbes as they pertain to responses to different weight-loss diets; however, the ways that diet, the gut microbiota, and long-term weight loss influence one another is not well understood.

Objectives

Our primary objective was to determine if baseline microbiota composition or diversity was associated with weight-loss success. A secondary objective was to track the longitudinal associations of changes to lower-carbohydrate or lower-fat diets and concomitant weight loss with the composition and diversity

SUBMITTER: Fragiadakis GK 

PROVIDER: S-EPMC7266695 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature