Fluid removal associates with better outcomes in critically ill patients receiving continuous renal replacement therapy: a cohort study.

ABSTRACT:

Background

Fluid overload is associated with morbidity and mortality in patients receiving renal replacement therapy (RRT). We aimed to explore whether fluid overload at initiation of RRT was independently associated with mortality and whether changes in cumulative fluid balance during RRT were associated with outcome.

Methods

We retrospectively analysed the data of patients who were admitted to the multidisciplinary adult intensive care unit (ICU) in a tertiary care centre in the UK between 2012 and 2015 and received continuous RRT (CRRT) for acute kidney injury for at least 24 h. We collected baseline demographics, body mass index (BMI), comorbidities, severity of illness, laboratory parameters at CRRT initiation, daily cumulative fluid balance (FB), daily prescribed FB ta

SUBMITTER: Hall A 

PROVIDER: S-EPMC7268712 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature