Ontology highlight
ABSTRACT:
SUBMITTER: Donegan JJ
PROVIDER: S-EPMC7272013 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Donegan Jennifer J JJ Boley Angela M AM Glenn Jeremy P JP Carless Melanie A MA Lodge Daniel J DJ
PloS one 20200604 6
Schizophrenia is a debilitating disorder affecting just under 1% of the population. While the symptoms of this disorder do not appear until late adolescence, pathological alterations likely occur earlier, during development in utero. While there is an increasing literature examining transcriptome alterations in patients, it is not possible to examine the changes in gene expression that occur during development in humans that will develop schizophrenia. Here we utilize three distinct rodent devel ...[more]